The main ingredient DMAE has only reported to prevent aging based on a small study by Dr.Perricone himself, the manufacturer of the brand. So the claims are not solidly supported.
Another abundant ingredient is glycolic acid (alpha hydroxy acid, AHAs). There is a lot of debate over AHA use in cosmetics. Concentration below 10% is considered useless. When the concentration is over 10%, AHA exfoliates upper layer skin by breaking the connective tissues between cells. This “chemical peel” reveals newer and more youthful looking skin. Also glycolic acid draws moisturizers into the newly-exfoliated skin surface. However, AHAs can leave skin extremely sensitive, especially to sun rays. So always wear sunscreen after use.
The product contains lecithin (Phosphatidylcholine) is the natural component of living cell membrane. Therefore it is readily aborbed by skin and is excellent for skin water reservior. So this product is very moisturizing.
There is no clear definition for the ingredient neuropeptides. Dr. Perricone claimed that neuropeptides are peptides released by brain cells as intercellular messengers. While manipulating the neuropeptides, neurotransmitters and hormones that are in the brain to help slow the aging process.
The neuro regulation is a complex process. The reality is that the size of typical peptides are too large to be absorbed through skin pores and reach epidermis. Epidermis is the layer beneath the surface of skin (dermis) and it is where collagen and elastin proteins reside. If the peptides can't be delivered there, they are simply wasted. Whether topical application of vague “neuropeptide” can combat aging is at best questionable. The peptides may fill in wrinkles but they are the last few ingredients so there may not be enough of them.
They put fragrance in there, which is unnecessary.
Safety alert: Cautious
review based on scientific information of the product ingredients.
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